Signaling Pathways

Cell signaling governs basic cellular activities and coordinates cell actions through a complex coordination of responses to cellular microenvironment. The disruption or errors found within this communication chain gives rise to various diseases and cancers. By understanding cell signaling, diseases may be treated more effectively and cures created.

The complex interaction of the activated receptor with other proteins inside the cell before the ultimate physiological effect of the ligand on the cell's behavior is produced is called signal transduction or cell signaling. Numerous cell signaling pathways exist, including Akt, NF-kB, and Notch signaling. Rockland produces antibodies that assist in research for a variety of these pathways.

  • Paracrine, endocrine and autocrine signaling
  • Direct signaling across gap junctions
  • Signaling pathways and cell surface receptors
  • Secondary messenger systems
  • Cell signaling pathway modeling

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