Call for Abstract

3rd Annual summit on Cell Signaling and Cancer Therapy, will be organized around the theme “”

Cell Signaling 2021 is comprised of 20 tracks and 0 sessions designed to offer comprehensive sessions that address current issues in Cell Signaling 2021.

Submit your abstract to any of the mentioned tracks. All related abstracts are accepted.

Register now for the conference by choosing an appropriate package suitable to you.


Cells respond to a multitude of signals in the extracellular environment, often by activating intracellular signaling pathways that elicit changes in cell function or behavior. These signaling pathways may be activated in response to growth factors, cytokines, or other signaling molecules, leading to intracellular activation of kinase pathways. CST offers a comprehensive portfolio of the highest quality products to interrogate molecular signaling networks. Replacing a disease-causing gene with a healthy copy of the gene. Inactivating a disease-causing gene that is not functioning properly. Introducing a new or modified gene into the body to help treat a disease


 


  • Track 1-1Map Kinase Signaling
  • Track 1-2Ca, cAMP, Lipid Signaling
  • Track 1-3AKT Signaling
  • Track 1-4Receptor Tyrosine Kinase Signaling
  • Track 1-5Growth factors and Cytokines


Stem Cell Research & Therapy is the major domain for translating analysis into stem cell therapies. An international peer-reviewed conference, it publishes high-quality open research access articles with a special stress on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The conference also provides reviews, viewpoints, commentaries, reports and strategies. They are some specified stem cells given below.



 


  • Track 2-1Adult stem cells
  • Track 2-2Embryonic stem cells
  • Track 2-3Induced pluripotent stem cells
  • Track 2-4Cancer stem cells
  • Track 2-5Stem cell differentiation, proliferation and migration
  • Track 2-6Cell culture and manufacture
  • Track 2-7Stem cell therapy/transplantation
  • Track 2-8Ethical, legal and social aspects


Stem cells are the basic materials of body cells from that all different cells will be specialized and functions are generated. Below the proper condition with in the body or a laboratory, stem cells divide to create a lot of cells called daughter cells.



These daughter cells will either become new stem cells (self-renewal) or else become specialized cells with a more specific function, such as blood cells, brain cells, heart muscle cells or bone cells. No different cell with in the body has the natural ability to generate new type of cell.



 


  • Track 3-1Increase understanding of how diseases occur
  • Track 3-2Embryonic stem cells
  • Track 3-3Test new drugs for safety and effectiveness
  • Track 3-4Adult cells altered to have properties of embryonic stem cells
  • Track 3-5Generate healthy cells to replace diseased cells (regenerative medicine)
  • Track 3-6Adult stem cells
  • Track 3-7Perinatal stem cells


Stem cells are constant cells found in cell living organisms that get separated through a cell division and then gets separate into a particular cell. The two properties of foundational microorganisms which are used to separate them in very body cell are self-restoration and proficiency. Because of their prospective job in different conducts, a foundational microorganism is subjected as inside and outside examination of Extensive Research Science.



 


  • Track 4-1Biology of Human Embryonic Stem Cells
  • Track 4-2Genomics and Genetics in Somatic Cell Biology
  • Track 4-3In-vitro culturing of Stem Cells
  • Track 4-4Cell signal in Somatic Cell Differentiation
  • Track 4-5Applications of Somatic Stem Cells


 Undefined cell treatment has been opened another way in the territory of medication  disclosure and improvement. Biopharmaceutical organizations have been working in interpreting fundamental utilizations of undefined cell advances in the medication improvement forms in order to diminish the high weakening rate generally arrange sedate applicants, which has been developing at a quick place in the previous decade.



Approach of unformed  microorganism advances has given new expectation to fabricate imaginative cell models. The always developing systems utilized for detachment of human/creature embryonic foundational microorganisms (ESCs), bone marrow-determined mesenchyme developed cells, umbilical line undifferentiated organisms, grown-up tissue-particular neural immature microorganisms and human instigated pluripotent foundational microorganisms (iPSC) have prompted the headway of varied high throughput and combinatorial screening advancements consequently supplementing the a  part of undifferentiated organism models in sedate disclosure.



 


  • Track 5-1Cancer Clinical Trails
  • Track 5-2Drug Screening Tools
  • Track 5-3Clinical Research And Bioethics
  • Track 5-4Drug Safety And Regulations
  • Track 5-5Stem Cell Biology And Regenerative Medicine


In recent years, stem cell nanotechnology has emerged as a replacement of exciting field. Experimental and Theoretical studies of interaction between nanostructures or nanomaterial’s and stem cells have created nice advances. The importance of nanotechnology, nanostructures, and nanomaterial’s to the elemental developments in stem cells-based therapies for injuries and degenerative diseases has been recognized. In general, the consequences of properties and structure of nanomaterials on the accretion and differentiation of stem cells became a replacement of integrative border in reconstruction medicine and material science



 


  • Track 6-1Nanoparticles: Cell Tracking, And Endocytosis
  • Track 6-2Nano vaccines
  • Track 6-3Nanotechnology For Creating Stem Cell Niche
  • Track 6-4Nanotechnology For Genetic Engineering
  • Track 6-5Nanoparticle Toxicity To Stem Cells
  • Track 6-6Nanomaterial’s And Nano engineering


Understanding the mechanisms that cause cell death is a critical aspect of cell biology, as many diseases involve aberrant regulation of cell death mechanisms. CST offers a variety of assays and reagents designed to enable evaluations of cell viability and cell death. LQT Syndromes.



 


  • Track 7-1Apoptosis
  • Track 7-2Autophagy
  • Track 7-3REDOX/Energy Metabolism
  • Track 7-4DNA Damage/Senescence


The skin gradually re-establishes itself for the duration of grown-up life, and the hair follicle experiences a never ending cycle of development and decay. Microorganisms (Stem Cell’s) lives in the epidermis and hair follicle guarantee the support of grown-up skin equilibrium and hair recovery; however they likewise take part in the fix of the epidermis after wounds.



 


  • Track 8-1Notch Signalling
  • Track 8-2Bone Morphogenetic Protein Signalling
  • Track 8-3Stem Cells With In Adult Skin Epithelium
  • Track 8-4Signalling And Stem Cell Fate Specification In The Skin


Cell proliferation is required for tissue growth, development, maintenance, and repair. Disruptions to the cell cycle that governs proliferation are a root cause of many diseases, most notably cancer. CST has a diverse catalog of antibodies and assays to study cell cycle progression and checkpoint control. Novel Stem Cell Therapy For Knees



 


  • Track 9-1Nucleotide metabolism
  • Track 9-2Cell Cycle
  • Track 9-3DNA Damage/Senescence


Cell therapy (also called cellular transplantation, cell therapy, or cytotherapy) is a therapy in which possible cells are injected, implant or embed into a patient in order to effectuate a medicinal effect, for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or grafting stem cells to regenerate diseased tissues.



Cell therapy commenced in the nineteenth century when scientists experimented by injecting animal material in a try to prevent and treat illness. However, such try didn’t produced any  positive benefit, the next research was  found in the mid twentieth century that human cells could be used to help prevent the human body rejecting transplanted organs, leading in time to successful bone marrow transplantation has become common practice in treatment for patients that have compromised bone marrow after disease, infection, radiation or chemotherapy. 



 


  • Track 10-1Allogeneic Cell Therapy
  • Track 10-2Autologous Cell Therapy
  • Track 10-3Xenogeneic Cell Therapy


The capability to make specific modifications to the human gene has been an objective in medical since; gene is the recognition of the basic unit for heredity. Therefore, gene therapy is defined as the capability of genetic improvement through the correction of modified genes or specific modifications that target therapeutic treatment. This therapy became possible through the advances of genetics and bioengineering that enabled manipulating vectors for delivery of extra chromosomal material to target cells. One of the major focuses on this technique is the optimization of delivery vehicles (vectors) that are mostly plasmas, unstructured or viruses. These viruses are more often investigated due to their excellence of infected cells and inserting their genetic material.


  • Track 11-1Substitution of the adenosine deaminize deficiency
  • Track 11-2Chemo protection
  • Track 11-3Improvement of immune function
  • Track 11-4Tumour removal
  • Track 11-5Enzymatic substitution
  • Track 11-6Cytokine release
  • Track 11-7Substitution of α 1-antitrypsin


Immunotherapy is considered as a type of cancer treatment that helps your immune system to fight against cancer. The immune system helps your body to fight with infections and other diseases. It is consists of organs and white blood cells and tissues of the lymph system.



Immunotherapy is a type of biological therapy. Organic therapy is a type of treatment that we use from the substances made from living organisms to treat cancer.



 


  • Track 12-1Monoclonal antibodies
  • Track 12-2Immune system modulators
  • Track 12-3Immune checkpoint inhibitors
  • Track 12-4T-cell transfer therapy


At the present scenario   Cancer therapies are not basing on surgery, radiation, and chemotherapy. Because all these three methods cause a risk damage to normal tissues or incomplete destruction of the cancer. Nano- therapy means to target chemotherapies and also collectively to cancerous cells and neoplasms, guide in surgical resection of tumour and enhance the therapeutic competence of radiation-based and the other current based treatment methods. All these together can decrease the risk to the patient and an increased probability of survival.



 


  • Track 13-1Delivering Chemotherapy
  • Track 13-2Nano-enabled Immunotherapy
  • Track 13-3Delivering Gene Therapy
  • Track 13-4Delivering or Augmenting Radiotherapy


Human gene therapy and its function for the treating the human genetic disorders, such as cystic fibrosis, cancer, and other diseases, are considered. Gene therapy is defined as a technique in which a functioning gene is stuck in into a human cell to correct a genetic error or else to introduce a new functioning to the cell. Many methods, including viral vectors and non-viral vectors, have been developed for both ex vivo and in vivo gene transfer into cells. There are several safety and ethical issues related to manipulating the human gene that need to be resolved. Current gene therapy efforts focus on gene insertion into stem cells only. The current human gene project provides the sequences of a vast number of human genes, leading to the identification, characterization, and understanding of genes that are responsible for many human diseases.


 


  • Track 14-1Replacing a disease-causing gene with a healthy copy of the gene
  • Track 14-2Bacterial vectors
  • Track 14-3Viral vectors
  • Track 14-4Inactivating a disease-causing gene that is not functioning properly
  • Track 14-5Plasmid DNA.
  • Track 14-6Introducing a new or modified gene into the body to help treat a disease
  • Track 14-7Patient-derived cellular gene therapy products
  • Track 14-8Human gene editing technology


Epigenetics is rising to eminence in biology as a mechanism by which environmental factors have intermediate-term effects on gene expression without changing the underlying genetic sequence. It can occur through the specific methylation of DNA bases and modification of histones. There are wide-feeding implications for the gene-environment contest and epigenetic mechanisms are causing a revaluation of many traditional concepts such as heritability. The reversible nature of epigenetics also provides conceivable treatment or prevention prospects for diseases previously thought hard-coded into the gene. Therefore, we consider how growing knowledge of epigenetics is altering our understanding of biology and medicine, and its implications for future research.



 


  • Track 15-1Covalent modifications
  • Track 15-2mRNA
  • Track 15-3MicroRNAs
  • Track 15-4Prions
  • Track 15-5Nucleosome positioning
  • Track 15-6Structural inheritance
  • Track 15-7RNA transcripts
  • Track 15-8sRNAs
  • Track 15-9Genomic architecture


Therapeutics Engineering assembles understanding of bodily responses to imputable materials and drug delivery devices. These focus on the biomaterial selection and fusion and also in depth study of drug design, manufacturing, and delivery. We will be getting trained in Nano-materials, material properties, transport phenomena, biochemical engineering, and metabolic engineering. Application areas include analyse therapeutics, biomimetic, and drug delivery systems.



 


  • Track 16-1Advancing technologies to detect and differentiate disease states and treatment responses (i.e., biomarkers) rapidly and precisely
  • Track 16-2Building and miniaturizing fully implantable, bio artificial devices to carry out the natural functions of failed organs
  • Track 16-3Delivering targeted, personalized cancer therapy to metastatic tumours
  • Track 16-4Creating methods and devices to deliver drugs across biological barriers, and to precisely target therapies to specific tissues and cells
  • Track 16-5Synthesizing injectable microstructure biomaterials to reduce functionally debilitating scarring
  • Track 16-6Developing metabolic imaging technologies to detect cancer biomarkers
  • Track 16-7Speeding genetic analysis of individual cells for disease biomarkers cells for disease biomarkers
  • Track 16-8Drug delivery for a leading cause of blindness
  • Track 16-9Developing low-cost sensors that detect subtle, early changes in health status, allowing for more rapid, effective interventions
  • Track 16-10Using microstructures to reduce debilitating scars after heart attacks
  • Track 16-11Building a solution for kidney failure


The U.S. Food and Drug Administration's (FDA's) new Paediatric Rule makes it more likely that children will receive improved treatment, because physicians will have more complete information on how drugs affect children and the suitable  doses for each age group (FDA, 1998e). The rule also allows FDA to require industry to test already marketed products in studies with paediatric populations in certain fascinating circumstances, such as when a drug is commonly prescribed for use in children but when the absence of adequate testing and labelling could be significant risks. The aim of this session is to examine many interrelated legal and regulatory issues, as well as the interrelated social and ethical concerns, in the evaluation of the effects of drugs and biologics on paediatric populations.



 


  • Track 17-1Anchoring Studies to
  • Track 17-2Placebo-Controlled Trials
  • Track 17-3Current Regulations Guiding Clinical Research
  • Track 17-4Consent, Assent, and Determination of Risk


Almost every cell and gene therapy the clinical trial is dissimilar in some way. Working with living organisms presents new and dissimilar challenges to the traditional clinical trial model. With over 400 decades CGT professionals globally, ICON has developed tools and best practices to transform CGT trial design and implementation. From site selection to study start up through implementation, ICON supply project management, clinical services, product-specific logistics solutions, data flow, regulatory strategy and central laboratory services.



 



Cell biology is the study of cell structure and function, and it spins around the concept that the cell is the basic unit of life. Centering on the cell permits a detailed understanding of the tissues and organisms that cells compose. A few organisms have only one cell, whereas others are organized into agreeable groups with huge numbers of cells. On the entire, cell biology centers on the structure and work of a cell, from the foremost common properties shared by all cells, to the special, profoundly complex functions particular to specialized cells.



 



Regenerative Medicine, the application of treatments developed to replace tissues damaged by injury or malady. These medicines may include the utilize of biochemical procedures to initiate tissue recovery specifically at the site of damage or the utilize of transplantation methods utilizing separated cells or stem cells, either alone or as a portion of a bio-artificial tissue.